If you’re not using ‘first purchase’ then you won’t have any issues and you can enable HPOS. I don’t expect issues with the ‘first purchase’, but we must test this. Will be in 2023-q1.
On your account page you can download 3.3.3-dev.1 which declares HPOS compatibility. As mentioned before, it hasn’t been 100% tested yet although I don’t expect any issues.